Structure of Azomycin, a New Antibiotic

Structure determination of pyracrimycin A, a new antibiotic substance.

mycin A on the basis of the chemical and physical properties and confirmed by the synthesis of the tetrahydro derivative III. Pyracrimycin A is a white crystalline substance, m. p. 215-216°G. The elemental analysis accounts for G7H10N2O(M. W. 138.17) confirmed by the M+ peak in the mass spectrum (Fig. 1). The IR spectrum (Fig. 2) is consistent with the presence of a primary amide group, as indi...

Isolation, characterization, and structure of rabelomycin, a new antibiotic.

The structure of gliovirin, a new antibiotic from Gliocladium virens.

In an earlier study, we reported the presence of the antibiotic, heptelidic acid, in the fungus, Gliocladium virens1). From this same organism we have isolated two additional compounds, one of which is selectively active against members of the Oomycetes2). We call this compound gliovirin (1). The second compound, L,L-phenylalanine anhydride (9), may be the biosynthetic precursor to gliovirin. G...

Isolation and structure of antibiotic U-68,204, a new thiolactone.

A new thiolactone-containing antibiotic U-68,204 was found to be produced by a soil actinomycete identified as Streptomyces thiolactonus UC 8478 (NRRL 15,439). The production, isolation, structure determination as well as the physical, spectroscopic and antibacterial properties of this C13H17NO3S compound are here reported. On the basis of these data, the antibiotic was identified as the 10-car...

Isolation and structure of a new polyether antibiotic, octacyclomycin.

In the course of a screening program for novel antibiotics showing antitumor activity, a cyclic peptide antibiotic sohbumycin was isolated from the culture broth of Streptomyces sp. No. 82-85, which had been isolated from a soil sample collected in Kanagawa prefecture, Japan. The isolation and physico-chemical properties of sohbumycin and fermentation and taxonomy of the producing organism, Str...